| Name Surname | Agata Mlynska |
| Institution | Qualification, academic degree, academic title | Year |
| Vilnius University | MSc in Biochemistry | 2012 |
| Vilnius University | PhD | 2018 |
| Employer | Occupation | Period |
| National Cancer Institute (NCI), Vilnius | Junior researcher | 2011-2018 |
| Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne | Doctoral assistant | 2014-2016 |
| National Cancer Institute (NCI), Vilnius | Researcher | 2018-2019 |
| National Cancer Institute (NCI), Vilnius | Senior researcher | 2019-- |
| Vilnius Gedimina technical university (VILNIUS TECH), Vilnius | Associate professor | 2020-- |
| Lausanne University Hospital (CHUV), Lausanne | Research assistant | 2021-2021 |
| Field of Science | Publications | Year |
| Biology | Pasukoniene V, Mlynska A, Steponkiene S, Poderys V, Matulionyte M, Karabanovas V, Statkute U, Purviniene R, Krasko JA, Jagminas A, Kurtinaitiene M, Strioga M, Rotomskis R. Accumulation and biological effects of cobalt ferrite nanoparticles in human pancreatic and ovarian cancer cells. Medicina. 2014;50(4):237-44. | 2014 |
| Biology | Strioga MM, Darinskas A, Pasukoniene V, Mlynska A, Ostapenko V, Schijns V. Xenogeneic therapeutic cancer vaccines as breakers of immune tolerance for clinical application: to use or not to use? Vaccine. 2014;32(32):4015-24. | 2014 |
| Biology | Liubaviciute A, Krasko JA, Mlynska A, Lagzdina J, Suziedelis K, Pasukoniene V. Evaluation of low-dose proton beam radiation efficiency in MIA PaCa-2 pancreatic cancer cell line vitality and H2AX formation. Medicina. 2015;51(5)302-6. | 2015 |
| Biology | Mlynska A, Povilaityte E, Zemleckaite I, Zilionyte K, Strioga M, Krasko J, Dobrovolskiene N, Peng MW, Intaite B, Pasukoniene V. Platinum sensitivity of ovarian cancer cells does not influence their ability to induce M2-type macrophage polarization. American Journal of Reproductive Immunology. 2018;80:e12996. | 2018 |
| Biology | Dobrovolskiene N, Pasukoniene V, Darinskas A, Krasko JA, Zilionyte K, Mlynska A, Gudleviciene Z, Miseikyte-Kaubriene E, Schijns V, Lubitz W, Kudela P, Strioga M. Tumor lysate-loaded Bacterial Ghosts as a tool for optimized production of therapeutic dendritic cell-based cancer vaccines. Vaccine. 2018;36:4171-4180 | 2018 |
| Biology | Krasko JA, Zilionyte K, Darinskas A, Dobrovolskiene N, Mlynska A, Riabceva S, Zalutsky I, Derevyanko M, Kulchitsky V, Karaman O, Fedosova N, Smychych TV, Didenko G, Chekhun V, Strioga M, Pasukoniene V. Postoperative unadjuvanted therapeutic xenovaccination with chicken whole embryo vaccine suppresses distant micrometastases and prolongs survival in a murine Lewis lung carcinoma model. Oncology Letters. 2018;15:5098-5104. | 2018 |
| Biology | Mlynska A, Salciuniene G, Zilionyte K, Garberyte S, Strioga M, Intaite B, Barakauskiene A, Lazzari G, Dobrovolskiene N, Krasko JA, Pasukoniene V. Chemokine profiling in ovarian cancer patients serum reveals candidate biomarkers for recurrence and immune infiltration. Oncology Reports. 2019;41:1238-52. | 2019 |
| Biology | Mlynska A, Vaisnore R, Rafanavicius V, Jocys S, Janeiko J, Petrauskyte M, Bijeikis S, Cimmperman P, Intaite B, Zilionyte A, Barakauskiene A, Meskauskas R, Paberale E, Pasukoniene V. A gene signature for subtyping of immune desert, excluded, and inflamed ovarian tumors. American Journal of Reproductive Immunology. 2020;84:e13244. | 2020 |
| Biology | Bosas P, Zaleskis G, Dabkevičiene D, Dobrovolskiene N, Mlynska A, Tikuišis R, Ulys A, Pašukoniene V, Jarmalaitė S, Jankevičius F. Immunophenotype Rearrangement in Response to Tumor Excision May Be Related to the Risk of Biochemical Recurrence in Prostate Cancer Patients. Journal of Clinical Medicine. 2021;10(16):3709. | 2021 |
| Date | Title of the conference and speech title |
| 2016-01-01 | Mlynska A, Povilaityte E, Zilionyte K, Pasukoniene V. Development and characterization of drug-resistant ovarian cancer cell sublines. Poster presentation, Best poster award. The COINS 2016 conference. Vilnius, Lithuania, Feb 2016. |
| 2016-01-01 | Mlynska A, Garberytė S, Žilionytė K, Lukoševičiūtė G, Intaite B, Pašukonienė. Immune related signature for identification of platinum-resistant ovarian cancer. Oral presentation. International Congress of Immunology. Melbourne, Australia, Sep 2016. |
| 2017-01-01 | Homicsko K, Cuendet M, Mlynska A, Moura B, Horak C, Hanahan D, Michielin O. Exploratory analysis of multiprotein serum predictors at baseline of progression-free survival of ipilimumab or ipilimumab and nivolumab in the Checkmate-069 study. Poster presentation. International ASCO 2017 congress. Chicago, USA, Jun 2017. |
| 2018-01-01 | Mlynska A, Salciuniene G, Zilionyte K, Intaite B, Barakauskiene A, Pasukoniene V. Serum chemokine profiling reveals candidate biomarkers for recurrence and immune infiltration in ovarian cancer. Poster presentation. 5th European Congress of Immunology, Amsterdam, Netherlands, Sep 2018. |
| 2021-01-01 | Mlynska A, Zymantaite E, Paberale E, Krasko JA, Pasukoniene V. Modeling of dendritic cell vaccines for ovarian cancer immunotherapy using cell lines of different molecular profiles. Oral presentation. 6th European Congress of Immunology (virtual), Sep 2021. |
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Foreign languages
|
A1/2: beginner; B1/2: advanced user; C1/2: proficient user; | ||
|---|---|---|---|
| Speaking | Understanding | Writing | |
| English | C2 | C2 | C2 |
| polish | C2 | C2 | C2 |
| russian | B2 | C1 | B1 |
| Level of studies | Subject title |
| Master Degree Studies | Immunotechnology |
| Bachelor Degree Studies | Fundamentals of Immunology |
| Institution | Country | Subject | Period |
| RESAL - Lemanic Animal Facility Network | Switzerland | Module on animal experimentation - FELASA B category | 2015-2015 |
| European Federation of Immunology Societies | Austria | Advanced flow cytometry | 2015-2015 |
| Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne | Switzerland | Combinatorial cancer immunotherapy preclinical trials | 2016-2017 |
| Ecole Polytechnique Federale de Lausanne (EPFL), Lausanne | Switzerland | Bioinformatic tools for transcriptomic analyses | 2020-2020 |
| Period | Project description |
| 2016-2018 | Primary implementer of the “Immunomodulating properties of bacteriophage derived dsRNA” project, funded by the Research Council of Lithuania (LMT Nr. TAP LLT-4/2016), 2016-2018. Estimated value - 52 000 Eur. |
| 2017-2018 | Primary implementer of the “Advanced immune-modulating medicinal product for cancer therapy” project, funded by the Lithuanian Business Support Agency (LVPA Nr. J05-LVPA-K-01-0179), 2017-2018. Estimated value - 540 000 Eur |
| 2018-2018 | Primary implementer of the “Development of a tool for cancer immunophenotyping and individualized immunotherapy modeling” project, funded by the Agency of Science, Innovation, and Technology (MITA Nr. 01.2.1-MITA-T-851-02-0017), 2018. Estimated value - 30 000 Eur. |
| 2019-2020 | Primary implementer of the “Development and clinical testing of autologous dendritic cell vaccines for ovarian cancer therapy” project, funded by the Lithuanian Business Support Agency (LVPA Nr. J05-LVPA-K-03-0076), 2019-2020. Estimated value - 1 090 000 Eur |
| 2019-2021 | Primary implementer of the “Immune modeling for infertility diagnostics and treatment” project, funded by the Lithuanian Business Support Agency (LVPA Nr. J05-LVPA-K-04-0016), 2019-2021. Estimated value - 1 200 000 Eur. |
| 2019-2019 | Project leader of the "Immunomodulatory properties of colon cancer cell lines" project, funded by the Research Council of Lithuania, 2019. Estimated value - 2000 Eur. |
| 2020-2022 | Primary implementer (postdoc researcher) of the "Development of transriptomic and histologic analysis-based tool for immune tumor subtyping and immunotherapy individualization" postdoc project, funded by the Research Council of Lithuania (Nr. 09.3.3-LMT-K-712-19-0094), 2020-2022. Estimated value - 85 000 Eur. |
| 2020-2021 | Project leader of the "Influence of stemness inhibitors on the immunomodulatory properties of colon cancer cells" project, funded by the Research Council of Lithuania, 2020-2021. Estimated value - 3000 Eur. |
| 2021-2024 | Project leader of the "Exploring the molecular mechanisms behind the effects of physical exercise on breast cancer prevention" project, funded by the Research Council of Lithuania (Nr. EEA-RESEARCH-164), 2021-2024. Estimated value - 150 000 Eur. |
| Period | Title |
| 2016-- | Member of Lithuanian Society of Immunologists |